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Bo Shen Selected Research

kallistatin

9/2014Novel role of kallistatin in vascular repair by promoting mobility, viability, and function of endothelial progenitor cells.
10/2012Depletion of endogenous kallistatin exacerbates renal and cardiovascular oxidative stress, inflammation, and organ remodeling.
11/2010Kallistatin attenuates endothelial apoptosis through inhibition of oxidative stress and activation of Akt-eNOS signaling.
8/2010Kallistatin inhibits vascular inflammation by antagonizing tumor necrosis factor-alpha-induced nuclear factor kappaB activation.
12/2009Kruppel-like factor 4 is a novel mediator of Kallistatin in inhibiting endothelial inflammation via increased endothelial nitric-oxide synthase expression.
5/2008Salutary effect of kallistatin in salt-induced renal injury, inflammation, and fibrosis via antioxidative stress.
12/2006Novel role of kallistatin in protection against myocardial ischemia-reperfusion injury by preventing apoptosis and inflammation.

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Bo Shen Research Topics

Disease

130Ulcerative Colitis
12/2022 - 04/2002
98Neoplasms (Cancer)
06/2022 - 02/2002
77Pouchitis
01/2022 - 04/2002
74Crohn Disease (Crohn's Disease)
01/2022 - 05/2004
60Inflammatory Bowel Diseases (Inflammatory Bowel Disease)
01/2021 - 05/2004
49Inflammation (Inflammations)
01/2023 - 05/2004
27Stomach Neoplasms (Stomach Cancer)
06/2022 - 10/2003
25Colitis
03/2022 - 01/2005
24Infections
01/2022 - 06/2009
23Pathologic Constriction (Stenosis)
12/2022 - 12/2004
23Acute Kidney Injury (Acute Renal Failure)
02/2022 - 04/2008
19COVID-19
09/2022 - 01/2020
19Sclerosing Cholangitis
06/2021 - 10/2005
18Fibrosis (Cirrhosis)
04/2022 - 05/2006
16Adenomatous Polyposis Coli (Familial Adenomatous Polyposis)
12/2022 - 10/2005
16Hepatocellular Carcinoma (Hepatoma)
01/2021 - 10/2005
11Lung Neoplasms (Lung Cancer)
05/2022 - 12/2012
11Hemorrhage
08/2021 - 11/2008
11Diarrhea
01/2020 - 01/2007
11Fistula
06/2019 - 12/2010
10Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung)
06/2022 - 07/2018
10Hypertension (High Blood Pressure)
11/2020 - 12/2012
9Neoplasm Metastasis (Metastasis)
12/2022 - 01/2006
9Ischemia
06/2022 - 04/2006
9Carcinogenesis
04/2022 - 12/2009
9Clostridium Infections
07/2020 - 01/2010
9Myocardial Infarction
06/2015 - 12/2006
8Breast Neoplasms (Breast Cancer)
12/2022 - 08/2012
8Disease Progression
05/2022 - 01/2005
8Chronic Kidney Failure (Chronic Renal Failure)
01/2021 - 06/2012
8Abscess
01/2019 - 10/2008
7Reperfusion Injury
06/2022 - 12/2006
7Adenocarcinoma
06/2022 - 02/2002
7Heart Failure
01/2022 - 09/2007
7Hypotension (Low Blood Pressure)
12/2021 - 11/2008
7Chronic Renal Insufficiency
01/2021 - 04/2016
7Hypertrophy
01/2021 - 05/2006
7Hypoxia (Hypoxemia)
01/2021 - 10/2008
7Rheumatoid Arthritis
12/2020 - 02/2011
7Anemia
11/2020 - 01/2007
6Parkinson Disease (Parkinson's Disease)
01/2022 - 01/2020
6Ischemic Stroke
01/2022 - 04/2006
6Necrosis
01/2020 - 09/2012
6Anastomotic Leak
12/2019 - 04/2011
5Liver Cirrhosis (Hepatic Cirrhosis)
04/2022 - 09/2010
5Body Weight (Weight, Body)
03/2022 - 01/2007
5Sepsis (Septicemia)
01/2022 - 10/2005
5Prolapse
10/2021 - 06/2010
5Colorectal Neoplasms (Colorectal Cancer)
01/2021 - 01/2017
5Critical Illness (Critically Ill)
01/2021 - 08/2017
5Obesity
01/2021 - 09/2013
5Abdominal Pain (Pain, Abdominal)
01/2020 - 05/2004
5Thrombosis (Thrombus)
02/2016 - 09/2010

Drug/Important Bio-Agent (IBA)

50Anti-Bacterial Agents (Antibiotics)IBA
01/2022 - 11/2003
37Proteins (Proteins, Gene)FDA Link
03/2022 - 02/2002
30Biomarkers (Surrogate Marker)IBA
05/2022 - 09/2012
20vedolizumabIBA
01/2022 - 01/2017
17MicroRNAs (MicroRNA)IBA
01/2021 - 10/2012
13Biological ProductsIBA
01/2021 - 02/2006
11Pharmaceutical PreparationsIBA
01/2022 - 01/2005
11Tissue Kallikreins (Tissue Kallikrein)IBA
01/2013 - 05/2006
10CytokinesIBA
09/2022 - 05/2008
10Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
01/2022 - 10/2009
9Glucose (Dextrose)FDA LinkGeneric
03/2022 - 07/2014
9SteroidsIBA
01/2020 - 08/2009
9Immunoglobulin G (IgG)IBA
01/2020 - 09/2010
9Kallikreins (Kallikrein)IBA
04/2010 - 04/2006
8Immunologic Factors (Immunomodulators)IBA
01/2019 - 01/2003
8Adrenal Cortex Hormones (Corticosteroids)IBA
01/2019 - 03/2012
8KininsIBA
04/2010 - 04/2006
7Messenger RNA (mRNA)IBA
01/2022 - 10/2005
7LigandsIBA
01/2022 - 05/2013
7CreatinineIBA
07/2021 - 03/2007
7Indicators and Reagents (Reagents)IBA
02/2021 - 10/2015
7SaltsIBA
01/2021 - 05/2006
7InsecticidesIBA
08/2019 - 01/2014
7Ciprofloxacin (Cipro)FDA LinkGeneric
01/2019 - 04/2002
7kallistatinIBA
09/2014 - 12/2006
6Long Noncoding RNAIBA
06/2022 - 01/2017
6RNA (Ribonucleic Acid)IBA
06/2022 - 01/2018
6Immune Checkpoint InhibitorsIBA
06/2022 - 01/2021
6Metronidazole (Metric)FDA LinkGeneric
01/2019 - 04/2002
5Complement System Proteins (Complement)IBA
09/2022 - 01/2014
5Immunoglobulins (Immunoglobulin)IBA
09/2022 - 03/2013
5AlbuminsIBA
07/2021 - 11/2016
5Infliximab (Remicade)FDA Link
03/2021 - 07/2008

Therapy/Procedure

144Restorative Proctocolectomy
12/2022 - 04/2002
101Therapeutics
12/2022 - 04/2002
47Colectomy
12/2022 - 12/2004
34Colonic Pouches (S Pouch)
01/2022 - 12/2004
28Renal Dialysis (Hemodialysis)
01/2022 - 01/2011
23Drug Therapy (Chemotherapy)
06/2022 - 10/2003
20Ileostomy
08/2020 - 09/2008
13Renal Replacement Therapy (Therapies, Renal Replacement)
01/2022 - 12/2011
11Immunotherapy
05/2022 - 01/2016
11Liver Transplantation
07/2017 - 01/2008
9Radiotherapy
06/2022 - 05/2013
8Biological Therapy
01/2019 - 08/2011
5Fecal Microbiota Transplantation
03/2022 - 02/2014
5Operative Surgical Procedures
10/2021 - 05/2012